TEST BACKGROUND
What is SIBO?
SMALL INTESTINE BACTERIAL OVERGROWTH Normally, bacteria are found in the trillions in the LARGE INTESTINE, where they perform various symbiotic functions for the human body. SIBO is a condition where bacterial overgrowth occurs in the absorptive area of the body the SMALL INTESTINE. The breath test is a simple, non-invasive test. After a 24 hours preparatory diet, the lactulose (or glucose or fructose) test substrate is swallowed. Lactulose is not absorbed and therefore may act as a food source for bacteria, if present, in the small intestine.
The bacteria may ferment the lingering substances and produce hydrogen and/or methane. These gasses may then be diffused into the bloodstream and exhaled via the breath. Breath samples are collected every 20 minutes for 3 hours. All tests use machines from QuinTron, the original manufacturer of BreathTracker, to measure both hydrogen and methane in a single sample of breath (alveolar air). Extensive quality control, including carbon dioxide measurements to assure an acceptable alveolar air sample, comply with the highest standards of analytical excellence. Effects of SIBO SIBO causes damage to the absorptive surface of the small intestine – the ability of the body to absorb nutrients from food.
The absorptive surface of the small intestine is likened to a shaggy carpet, with finger-like protrusions called villi. The surface of the villi contain microvilli, which act as the interface of absorption—microvilli secrete enzymes called “brush border enzymes” which break starches into single molecules and proteins into single amino acids, so these can be absorbed. Small Intestine – absorbing nutrients from food
Glucose is like extra food for bacteria. It gets absorbed in the beginning of the small intestine. If the test shows positive for glucose, it can help confirm SIBO. But there's a problem with the glucose test. Glucose gets absorbed fast, so it might not catch bacteria that are further down in the small intestine. Some doctors think using both lactulose and glucose together is better for finding SIBO accurately.
This test doesn't miss anything. By using three methods together, it's really good at finding fermentation and gas if they're there. Also, if your test shows you have SIBO, it can tell you if you should avoid fructose in your diet while treating it. If your symptoms are really bad, it's a good idea to do this combined test to help figure out what foods to avoid.